Research Hit: How do Lonely Brains Differ from Wise Brains?
Research shows different brain responses in social situations and might create self reinforcing loops
From the Archives:
I reported previously how wise people are less likely to be lonely, and how lonely people are less likely to be wise. There seems to be strong inverse relationship to these two characteristics — so why, and what drives this in the brain?
Recent research has given us some answers to this by focusing on how wise and lonely people process emotions. The researchers from University of California San Diego School of Medicine showed that the brains of lonely and wise people process some emotions in opposing ways.
The research included 147 people from the ages of 18–85 and involved making decision on directions of arrows when combined with distractors that were pictures of faces expressing different emotions. This was combined with EEG measurements measuring brain activity. The results are fascinating.
Those higher on loneliness responded slower when presented with angry faces showing higher sensitivity to angry or threatening stimuli.
Those higher on wise traits responded quicker when presented with happy faces, showing positive responses to positive stimuli
This opposing relationship is fascinating, showing how social responses are different. A question to answer is that is this a self-fulfilling prophecy? Lonely people responding to threatening faces and situations more, and therefore withdrawing more from society.
Looking into the brain, the region that was identified as being most active in both the lonely and the wise, is a brain region called the temporal-parietal junction (TPJ). This regions is involved in theory of mind — being able to put oneself in another's shoes. this was highest activated in the brains of those who were more lonely and those who were more wise.
The difference is that those who are wise are responding more to happiness and those who are lonely are responding more to threat.
This is important because it gives us a better grip on what loneliness is in the brain and how to create interventions for this. This points to the fact that just having contact to people may not help people who are lonely because of their sensitivity to threat, so intervening by minimising their sensitivity to threat may produce the largest impacts — this because loneliness has been shown to have numerous negative impacts on health and mental health.
The researchers are looking to study this further — I look forward to the results!
Reference
Gillian Grennan, Pragathi Priyadharsini Balasubramani, Fahad Alim, et al.
Cognitive and Neural Correlates of Loneliness and Wisdom during Emotional Bias
Cerebral Cortex, Volume 31, Issue 7, July 2021, Pages 3311–3322
https://doi.org/10.1093/cercor/bhab012